1. mkdir ~/.pip/
2. cat ~/.pip/pip.conf
   • [global]
   • index-url = http://pypi.douban.com/simple
   • download_cache = ~/.cache/pip
   • [install]
   • use-mirrors = true
   • mirrors = http://pypi.douban.com/
3. 一些可选的参数
   • trusted-host = pypi.douban.com
   • timeout=6000
     来源： http://my.oschina.net/u/2012873/blog/648152

• On Unix the default configuration file is: $HOME/.config/pip/pip.conf which respects the XDG_CONFIG_HOME environment variable.
• On Mac OS X the configuration file is $HOME/Library/Application Support/pip/pip.conf.
• On Windows the configuration file is %APPDATA%\pip\pip.ini.

There are also a legacy per-user configuration file which is also respected, these are located at:

• On Unix and Mac OS X the configuration file is: $HOME/.pip/pip.conf
• On Windows the configuration file is: %HOME%\pip\pip.ini

You can set a custom path location for this config file using the environment variable PIP_CONFIG_FILE.

Inside a virtualenv:

• On Unix and Mac OS X the file is $VIRTUAL_ENV/pip.conf
• On Windows the file is: %VIRTUAL_ENV%\pip.ini